Olefin Metathesis Catalysts

Dual tag

About us
CAACatalyst
Z-Stereo

Olefin Metathesis Catalysts

for net zero value chain

CAACatalyst
Z-Stereo

Purity Optional,

Performance Guaranteed

High Z-Selectivity Under Extreme Conditions

Olefin metathesis catalysts for net zero value chain

for net zero value chain

Purity Optional,

Performance Guaranteed

CAACatalyst

High Z-Selectivity Under Extreme Conditions

Z-Stereo
ImageImage

Why
we create olefin metathesis catalysts?

Groundbreaking olefin metathesis catalysts open new possibilities for sustainable development across industries, as recognized by the 2005 Nobel Prize. We are determined to leverage this innovative discovery to create more efficient and environmentally friendly technologies, addressing global challenges and striving for continual improvements in every field of application.

What
we have done so far?

Professor Karol Grela's team has significantly impacted the field of olefin metathesis, with numerous discoveries and over 15 patent families. Their pioneering work led to the creation of the nitro-Grela catalyst, breaking a U.S. monopoly and facilitating the synthesis of complex chemicals. This innovation prompted the founding of Apeiron Synthesis, which collaborates with industry giants like Orlen SA, driving advancements in green technologies. The team's contributions extend beyond commercial success, marking a pivotal shift in sustainable chemical manufacturing and enhancing global access to greener solutions.

Detailed chemical structure of the Nitro-Grela catalyst, a green powder developed by Professor Karol Grela's team at the University of Warsaw. The catalyst, with the chemical formula C31H37Cl2N3O3Ru and a molecular weight of 671.62 g/mol, is a ruthenium-based compound known for its high selectivity and efficiency in cross metathesis (CM) reactions. It enables high conversion rates and selectivity in reactions involving electron-deficient partners and sterically hindered olefins. This versatile catalyst is used in various industries, including pharmaceuticals, polymers, fine chemicals, household chemicals, flavors and fragrances, and agrochemicals. Nitro-Grela allows reactions to occur at lower temperatures with reduced catalyst load compared to competitors like Grubbs-II and Hoveyda-Grubbs II, making it a cost-effective and environmentally friendly option.

Nitro-Grela

Who
can benefit?

Chemical
Manufacturing
Oil
&
Gas
Pharmaceutical
Industry
Flavor
&
Fragrances
Pheromone
Synthesis
Polymer
Manufacturing
Cosmetic
Industry
Fine Chemicals
Industry
Agrochemical
Industry

Our olefin metathesis catalysts

CAACatalyst
Image

Purity Optional,

Performance Guaranteed

Z-Stereo

High Z-Selectivity Under Extreme Conditions

Image

Usable in concetrations down to

0.5 ppm

Easy and scalable ligands and catalyst synthesis

Green chemistry

in obtaining the valuable product

9-DAME

activity and selectivity

>95%

780 000 TON

Image

Green chemistry

Image

Easy and scalable ligands and catalyst synthesis

Usable in concetrations down to

100 ppm

activity and selectivity

>95%

High selectivity up to

150 °C

Team
from University of Warsaw

Groundbreaking olefin metathesis catalysts open new possibilities for sustainable development across industries, as recognized by the 2005 Nobel Prize. We are determined to leverage this innovative discovery to create more efficient and environmentally friendly technologies, addressing global challenges and striving for continual improvements in every field of application.

Adrian Sytniczuk

>65 publications

10 patents

17 H-Index

Assistant professor at University of Warsaw

Anna Kajetanowicz
Anna Kajetanowicz coauthor of Olefin Metathesis Catalyst innovations, including Z-stereoretentive olefin metathesis catalysts and Caac catalysts.Photo of Professor Karol Grela, a renowned chemist specializing in the synthesis of organic and organometallic compounds. Professor Grela leads the Laboratory of Metalloorganic Synthesis at the Biological and Chemical Research Centre, Faculty of Chemistry, University of Warsaw. He is also affiliated with the Institute of Organic Chemistry of the Polish Academy of Sciences. With over 230 publications and 15 patents, his work on ruthenium catalysts for olefin metathesis has earned him numerous awards and international recognition, including the Polish Science Foundation Prize in 2014. His catalysts are highly valued in various industries, including pharmaceuticals, polymers, fine chemicals, household chemicals, flavors and fragrances, agrochemicals, and cosmetics.

>230 publications

15 patents

50 H-Index

Professor at University of Warsaw

Karol Grela
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Filip Struzik
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Łukasz Grzesiński
Image of technology broker Rafał Orlowicz-Murawski who is responsible for business contacts and tech transfer of olefin metathesis catalysts created by professor Karol Grela and his team from University of Warsaw. Icon

Technology Broker

Rafał Orłowicz-Murawski
Logo of the Centre for Technology and Knowledge Transfer at the University of Warsaw, highlighting its role in technology transfer, intellectual property protection, and fostering academic innovation. The center connects university research with business, ensuring the commercial application of scientific discoveries. Logo of the University of Warsaw featuring a white eagle and the text "University of Warsaw - Excellence Initiative Research University." The university focuses on teaching, research, and the transfer of knowledge and technology, with notable achievements in mRNA technology transfer to BioNTech.